Business
Farmaci biotech: top 50
Ecco l’elenco dei 50 biofarmaci più venduti al mondo nell’anno 2011 che Ronald A.Rader, presidente del Biotechnology Information Institute, ha stilato per la rivista “Contract Pharma”.
Sono di seguito riportati il nome del farmaco, la sua descrizione, la casa farmaceutica produttrice, e i miliardi di dollari fatturati nel 2011 per tipologia di farmaco.
| Marchio | Descrizione | Società | Ricavi 2011 |
| Humira | TNF Mab, rDNA, human | Abbott | $7,932 |
| Enbrel | TNF Receptor-IgG Fc, rDNA | Amgen, Pfizer | $7,870 |
| Remicade | TNF Mab, rDNA | J&J, Merck | $7,157 |
| Avastin | VEGF Mab, rDNA | Genentech/Roche | $6,596 |
| Rituxan | CD20 Mab, rDNA | Genentech/Roche, Biogen | $6,596 |
| Herceptin | HER2 receptor Mab, rDNA | Genentech/Roche | $5,770 |
| Lantus | Insulin glargine, rDNA | Sanofi | $5,190 |
| Neulasta | G-CSF, rDNA, PEG- | Amgen, Roche | $3,950 |
| Epogen/Procrit | EPO, rDNA | Amgen, J&J | $3,730 |
| Lucentis | VEGF Mab Fab, rDNA | Genentech/Roche Novartis | $3,723 |
| Prevnar 13 | Pneumococcal Vaccine(13) | Pfizer | $3,330 |
| Aranesp | EPO, darbo-, rDNA | Amgen | $2,997 |
| Avonex | Interferon beta-1a, rDNA | Biogen Idec, Merck | $2,700 |
| Humalog | Insulin lispro, rDNA | Lilly, Roche | $2,367 |
| NovoLog | Insulin aspart, rDNA | Novo Nordisk | $2,274 |
| Rebif | Interferon beta-1a, rDNA | Merck KGaA | $2,235 |
| Advate | Factor VIII, rDNA | Baxter | $2,210 |
| Novolin | Insulin, rDNA | Novo Nordisk | $1,916 |
| Erbitux | EGF receptor Mab, rDNA | Bristol-Myers Squibb | $1,820 |
| Botox | Botulinum Toxin A | Allergan | $1,775 |
| Tysabri | Integrin Mab, rDNA | Biogen Idec, Elan | $1,500 |
| Pegasys | Interferon alfa-2a, rDNA, PEG- | Roche | $1,476 |
| Betaseron | Interferon betaser, rDNA | Bayer | $1,476 |
| NovoSeven | Factor VIIa, rDNA | Novo Nordisk | $1,470 |
| Neupogen | G-CSF, rDNA | Amgen & Roche | $1,440 |
| Kogenate | Factor VIII, rDNA | Bayer | $1,420 |
| Levemir | Insulin detemir, rDNA | Novo Nordisk | $1,365 |
| Humulin | Insulin, rDNA/Lilly | Lilly | $1,249 |
| Gardasil | HPV vaccine, rDNA | Merck | $1,209 |
| Xolair | Immunoglobulin E Mab, rDNA | Genentech/Roche Novartis | $1,140 |
| Victoza | Glucagon-like peptide-1, rDNA | Novo Nordisk | $1,060 |
| NeoRecormon | EPO beta, rDNA | Roche | $985 |
| Synagis | RSV Mab, rDNA | MedImmune/AstraZeneca | $980 |
| Varivax II | Varicella virus vaccine | Merck | $975 |
| Fortéo | Parathyroid hormone (1-34) | Lilly | $950 |
| Genotropin | Somatropin, rDNA | Pfizer | $940 |
| Orencia | CTLA4-Ig, rDNA | Bristol-Myers Squibb | $917 |
| Norditropin | Somatropin, rDNA | Novo Nordisk | $890 |
| Eprex | EPO, rDNA | J&J | $809 |
| Soliris | Complement C5 Mab, rDNA | Alexion | $783 |
| Stelara | IL-12/23 Mab, rDNA | J&J | $740 |
| Cerezyme | Glucocerebrosidase, rDNA | Genzyme/Sanofi | $720 |
| BeneFIX | Factor IX, rDNA | Pfizer | $695 |
| Actemra | IL-6 receptor Mab, rDNA | Genentech/Roche | $680 |
| Simponi | TNF Mab, rDNA | J&J | $674 |
| PEG-Intron | Interferon alfa-2b, rDNA, PEG- | Merck | $657 |
| RotaTeq | Rotavirus vaccine | Merck | $651 |
| Gonal-f | FSH rDNA | Merck KGaA | $645 |
| Myozyme | Glucosidase, rDNA | Genzyme/Sanofi | $543 |
| Pulmozyme | DNase, rDNA | Genentech/Roche | $540 |
| Menactra | Meningococcal vaccine | Sanofi | $530 |
| Follistim | FSH rDNA | Merck | $530 |
| Lumizyme | Glucosidase, rDNA | Genzyme/Sanofi | $530 |
| Vectibix | EGF receptor Mab | Amgen | $525 |
| Xyntha/ReFacto | Factor VIII, rDNA | Pfizer | $504 |
| Recombivax HB | Hepatitis B Vaccine, rDNA | Merck | $500 |
| Engerix-B | Hepatitis B Vaccine, rDNA | GlaxoSmithKline | $500 |
